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The familiar treadmill stress test that has
diagnosed heart disease in
millions of Americans is being made obsolete by
the computer age.
A
new generation of X-ray CT scans that appeared
in the past two
years can detect clogged heart arteries more
accurately than older methods,
doctors say, and can detect the most lethal
types of
blockages, which don't show up on stress tests.
In
addition, some CT specialists contend that the
new computed tomography scan
is as powerful as the angiogram, currently the
prime tool for finding clogged
arteries but one that is invasive and can
cause complications.
"CT is better than anything we have now that is
noninvasive," said
Dr. Michael Yue-Hua Shen, a heart imaging
specialist at Cleveland Clinic in Weston. "This
is where we're going in the future."
Since 2001, when CT scans were improved to the
point that they could make
clear images of the heart, the number of cardiac
CTs has climbed
to more than 1 million per year nationwide --
and is rising -- compared
with 10 million stress tests and 2.2 million
angiograms.
Doctors are regularly using CT scans to assess
patients' blockages and more
accurately determine whether they need
cholesterol-lowering medicine.
The scans help doctors tailor treatment to the
patient's
exact needs, rather than using a general
approach, Shen said.
Still, some heart specialists question the value
of CT scans for heart
disease.
Dr. Edward Martin at the Oklahoma Heart
Institute in Tulsa favors
MRIs, saying the accuracy is almost as good and
the image is created
by nondamaging magnetic beams instead of X-rays.
Dr. Roger Blumenthal, director of preventive
cardiology at Johns
Hopkins University, said angiograms still have
slightly better resolution
than CT in measuring blockages, especially ones
hardened by calcium.
Boca Raton salesman Norman Levi, 62, said he
might owe his life to a
CT scan. Levi felt chest pain while walking his
dog -- frightening for a
man whose parents died without warning from
first-time heart attacks. A stress test was
inconclusive. His doctor suggested heartburn
pills. No
help. Later, a CT scan found the culprit: a 90
percent blockage in an artery. |
"The
CT scan saw something the stress test didn't find,"
Levi said.
And it
was done within minutes, without surgery. Doctors
injected Levi with dye, made
a 20-second X-ray scan with a CT and reaped dozens
of detailed, computerized images of his heart and
vessels.
For
years, doctors have relied heavily on the stress
test and the angiogram
to find heart disease, the nation's top killer and
the cause of 1.1
million heart attacks per year.
Stress
tests use sound waves or radioactive dye to measure
blood flow to
the heart while the patient is resting or
exercising. If a problem is
found, patients usually get an angiogram. Doctors
make an incision at
the groin, thread a thin tube through an artery,
inject dye and examine the
blood vessels with an X-ray. They can see if the
flow of blood is
being blocked in an artery narrowed by plaque,
deposits of fat caused
by cholesterol.
But
there's a hitch in this approach.
"Half of the people who have
heart attacks never have narrowing of the
blood vessels. Something else is going on," said
Dr. Claudio Smuclovisky,
a CT specialist at South Florida Imaging in Boca
Raton.
Doctors now know that plaque doesn't just bulge into
the vessel, it
bulges out, undetectable to stress tests and
angiograms. Plaque is dangerous
not just because it blocks the artery but because it
ruptures, prompting the body to form big clots that
block the vessel.
Outward bulges are the more dangerous type. Studies
show about 70 percent of those
with outward bulges have heart attacks vs. 30
percent of those with
inward bulges. CT scans can see the outward bulges.
"If
the stress test is negative, the doctor is going to
tell you that you're fine. Well,
maybe not," Shen said. "With the CT, we can see the
plaque.
We can be more aggressive in treating it."
CT
scans have another advantage: They are not invasive.
One percent of
angiograms, also called cardiac catheterizations,
cause complications such as
stroke, internal bleeding, anesthesia reactions and
in about 1 in 1,000 cases, death.
Stress tests will
never fade away, some specialists say, because they
better measure the heart at work.
"You're never going to have any one test taking over
the landscape," Martin said.
Even
fans of CT heart scans say they expose patients to
too much radiation to be used as a
routine screening test for healthy people. The
scan delivers 8 to 12 millisievert of radiation,
about three times the
expose we get annually from nature. A stress test
using nuclear dye is about the
same; an angiogram is a little less.
"The
radiation risk from CT is significant," Shen said.
But
proponents of heart CTs predict rapid growth of new
uses and
wider acceptance. Most insurers cover CT heart scans
if deemed
medically needed.
Cardiologists are using CTs to decide whether
patients with borderline
heart problems need angiograms, about one-quarter of
which find no
heart disease. Doctors said CT scans at $700 to
$1,000 each can
spare thousands of people from the risk and expense
of angiograms
costing $5,000 to $15,000.
A May
study in the Journal of the American Medical
Association found
heart CTs as accurate as angiograms, catching 87 to
99 percent of blockages in German
heart patients.
Cardiologist
Seth Baum
in Boca Raton is among a growing number using
CT scans to decide whether a patient needs
cholesterol drugs, which
can damage the liver.
Scans
have found patients deemed to be at low risk for
heart disease
who have dangerous plaque and need to be on
medication, Baum said, as well as
higher-risk patients who are free of plaque and can
stick with safer
therapy such as niacin.
"If
you're 40 and with elevated cholesterol but no heart
disease on the CT, it might be wise to keep you off
the medication and just put you on [a] diet
and exercise [regimen]," said radiologist
Smuclovisky, who took himself
off cholesterol drugs after a clean CT.
Shen's
team in Weston scanned 77 heart patients as part of
a study
now being prepared. They found dangerous plaque in
48 percent of
those rated low risk based on family history,
cholesterol and other
factors. About 20 percent of the patients had enough
plaque to
justify starting medication, Shen said.
In
some parts of the country, emergency room doctors
use CT scans
to check patients with chest pain, hoping to quickly
confirm or rule out heart
attacks, torn vessels or blood clots that could be
fatal. A Mayo Clinic study
says hospitals waste $10 billion a year by admitting
chest- pain patients
who prove to have no heart problems.
CT
heart scans have found serious diseases by
coincidence. Smuclovisky said he
has found cancer in lungs and livers. A University
of Michigan study in May reported that CT heart
scans found serious tumors, clots and
aneurysms in 43 of 98 scan patients.
Fort
Lauderdale radiologist Charles Tate III went for a
CT heart scan in August because he was feeling
tired. The test proved his heart was fine,
he said, but found a potentially fatal blood clot in
his left lung that
was removed immediately.
"In
days gone people would have walked around with these
things and never have known
it unless something happened," Tate said. "Now we
can know." |